From the Literature


Published: Jan 2011

Hemostatic effects of fresh frozen plasma may be maximal at red cell ratios of 1:2.

Davenport R, Curry N, Manson J, et al.

J Trauma 2011;70(1):90-96.

Pub Med
NATA rating :


S. Kozek-Langenecker



The authors report the preliminary findings of the first prospective observational cohort study on the hemostatic effects of different FFP:PRBC ratios in trauma patients. Effects were highest in patients receiving a ratio between 1:2 to 3:4. Individual response to FFP was patient-dependent and highest in patients with coagulopathy – point-of-care monitoring may help in identifying patients\' needs.

- Sibylle Kozek-Langenecker