From the Literature

Published: Dec 2012

Voils SA, Baird B

Systematic review: 3-factor versus 4-factor prothrombin complex concentrate for warfarin reversal: does it matter?
Thromb Res 2012;130:833-840.

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NATA REVIEW:
Immediate reversal of the anticoagulant effect of vitamin K antagonists, for example in case of intracranial...
REVIEW by:
M. Levi

Published: Nov 2012

Schoorl M, van der Gaag D, Bartels PC

Effects of iron supplementation on red blood cell hemoglobin content in pregnancy.
Hematol Rep 2012;4:e24.

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NATA REVIEW:
The authors present an interesting study evaluating the effectiveness of iron supplements in late pregnancy....
REVIEW by:
C. Breymann

Published: Nov 2012

Roberts I, Perel P, Prieto-Merino D, et al.

Effect of tranexamic acid on mortality in patients with traumatic bleeding: prespecified analysis of data from randomised controlled trial.
BMJ 2012;345:e5839.

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NATA REVIEW:
The CRASH-2 study, published in 2010, showed that treatment with tranexamic acid resulted in a reduction of mortality...
REVIEW by:
M. Levi

Published: Nov 2012

Okam MM, Mandell E, Hevelone N, Wentz R, Ross A, Abel GA

Comparative rates of adverse events with different formulations of intravenous iron.
Am J Hematol 2012;87:E123-124.

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NATA REVIEW:
Although this is a retrospective analysis of intravenous iron use in a large hospital system, it is the Harvard...
REVIEW by:
M. Auerbach

Published: Sep 2012

Weber CF, Görlinger K, Meininger D, et al.

Point-of-care testing: a prospective, randomized clinical trial of efficacy in coagulopathic cardiac surgery patients.
Anesthesiology 2012;117:531-547.

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NATA REVIEW:
The study presented by Weber and coworkers is the first prospective, randomized and controlled clinical trial...
REVIEW by:
O. Habler

Published: Sep 2012

Barish CF, Koch T, Butcher A, Morris D, Bregman DB

Safety and efficacy of intravenous ferric carboxymaltose (750 mg) in the treatment of iron deficiency anemia: two randomized, controlled trials.
Anemia 2012:172104.

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NATA REVIEW:
In this article, the authors present data from two phase 3, open-label, randomized, controlled, multicenter trials...
REVIEW by:
M. Muñoz

Published: Aug 2012

Afdhal NH, Giannini EG, Tayyab G, et al.

Eltrombopag before procedures in patients with cirrhosis and thrombocytopenia.
N Engl J Med 2012;367:716-724.

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NATA REVIEW:
This is an important study aimed at determining if administration of eltrombopag reduces the need for platelet...
REVIEW by:
P. Rebulla

Published: Aug 2012

Vaucher P, Druais PL, Waldvogel S, Favrat B

Effect of iron supplementation on fatigue in nonanemic menstruating women with low ferritin: a randomized controlled trial.
CMAJ 2012;184:1247-1254.

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NATA REVIEW:
The authors present a well-conducted randomized study of the effect of iron administration to non-anemic menstruating...
REVIEW by:
A. Maniatis

Published: Jul 2012

Long H, Yi JM, Hu PL, et al.

Benefits of iron supplementation for low birth weight infants: a systematic review.
BMC Pediatr 2012;12:99.

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NATA REVIEW:
Long and colleagues performed a systematic review on the benefits of iron supplementation in low-birth-weight...
REVIEW by:
J. Lacroix

Published: Jul 2012

Qian F, Osler TM, Eaton MP, et al.

Variation of blood transfusion in patients undergoing major noncardiac surgery.
Ann Surg 2012; Jul 13 [Epub ahead of print].

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NATA REVIEW:
This large observational study shows that institutional variability in current transfusion practices for commonly...
REVIEW by:
Y. Ozier

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