From the Literature

Published: Apr 2011

Goobie SM, Meier PM, Pereira LM, et al.

Efficacy of tranexamic acid in pediatric craniosynostosis surgery: a double-blind, placebo-controlled trial.
Anesthesiology 2011;114(4):862-871.

#

NATA REVIEW:
Prohemostatic treatment has repeatedly been shown to be effective in reducing perioperative blood loss and...
REVIEW by:
M. Levi

Published: Apr 2011

Taguchi K, Ogaki S, Watanabe H, et al.

Fluid resuscitation with hemoglobin vesicles prevents Escherichia coli growth via complement activation in a hemorrhagic shock rat model.
J Pharmacol Exp Ther 2011;337(1):201-208.

#

NATA REVIEW:
The paper by Takaguchi et al. reports the effects of hemoglobin vesicles (HbVs) developed as oxygen-carrying...
REVIEW by:
M. Intaglietta

Published: Mar 2011

Lauscher P, Kertscho H, Meissner A, Zacharowski K, Habler O, Meier J

Hyperoxic ventilation improves survival in pigs during endotoxaemia at the critical hemoglobin concentration.
Resuscitation 2011;82(4):473-480.

#

NATA REVIEW:
This experimental study evaluated the effects of hyperoxic ventilation (FiO2 1.0) on survival in anesthetized...
REVIEW by:
P. Van der Linden

Published: Mar 2011

Schoechl H, Nienaber U, Maegele M, et al.

Transfusion in trauma: thromboelastometry-guided coagulation factor concentrate-based therapy versus standard fresh frozen plasma-based therapy.
Crit Care 2011;15(2):R83.

#

NATA REVIEW:
This retrospective observational study compared two treatment concepts in major trauma patients: an FFP-based...
REVIEW by:
S. Kozek-Langenecker

Published: Mar 2011

Afshari A, Wikkelso A, Brok J, Moller AM, Wetterslev J

Thrombelastography (TEG) or thromboelastometry (ROTEM) to monitor haemotherapy versus usual care in patients with massive transfusion.
Cochrane Database Syst Rev 2011;3:CD007871.

#

NATA REVIEW:
Thrombelastography (TEG) and thrombelastometry (ROTEM) represent two in-vitro methods to measure...
REVIEW by:
O. Habler

Published: Mar 2011

Roberts I, Shakur H, Afolabi A, et al.

The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
Lancet 2011;377(9771):1096-1101.

#

NATA REVIEW:
The randomized placebo-controlled CRASH-2 study, published in 2010, showed that treatment with tranexamic...
REVIEW by:
M. Levi

Published: Mar 2011

Morrison CA, Carrick MM, Norman MA, et al.

Hypotensive resuscitation strategy reduces transfusion requirements and severe postoperative coagulopathy in trauma patients with hemorrhagic shock: preliminary results of a randomized controlled trial.
J Trauma 2011;70:652-663.

#

NATA REVIEW:
Morrison and coworkers present an interim analysis (90 out of 271 planned patients) of the results of their...
REVIEW by:
O. Habler

Published: Mar 2011

Henry DA, Carless PA, Moxey AJ, et al.

Anti-fibrinolytic use for minimising perioperative allogeneic blood transfusion.
Cochrane Database Syst Rev 2011;(3):CD001886.

#

NATA REVIEW:
This review does not present new data for those who are familiar with the use of antifibrinolytics in the...
REVIEW by:
J.-F. Hardy

Published: Mar 2011

Bhandari S

A hospital-based cost minimization study of the potential financial impact on the UK health care system of introduction of iron isomaltoside 1000.
Ther Clin Risk Manag 2011;7:103-113.

#

NATA REVIEW:
This is an interesting paper that examines cost savings achieved by rapid administration of large doses of...
REVIEW by:
M. Auerbach

Published: Mar 2011

Singh R, Visintainer PF, Frantz ID, 3rd, et al.

Association of necrotizing enterocolitis with anemia and packed red blood cell transfusions in preterm infants.
J Perinatol 2011;31(3):176-182.

#

NATA REVIEW:
Singh et al. report an association between anemia, red blood cell (RBC) transfusion and necrotizing...
REVIEW by:
J. Lacroix

Pages