From the Literature

Published: Sep 2019

Downey LA, Andrews J, Hedlin H, et al.

Fibrinogen concentrate as an alternative to cryoprecipitate in a postcardiopulmonary transfusion algorithm in infants undergoing cardiac surgery: a prospective randomized controlled trial.
Anesth Analg 2019; Sep 3 [Epub ahead of print].

#

NATA REVIEW:
This is an excellent multicentre prospective randomised trial evaluating the efficacy of fibrinogen concentrate...
REVIEW by:
E. Adams

Published: Sep 2019

Callum JL, Yeh CH, Petrosoniak A, et al.

A regional massive hemorrhage protocol developed through a modified Delphi technique.
CMAJ Open 2019;7:E546-E561.

#

NATA REVIEW:
The authors noted that large academic centres are very likely to have a massive haemorrhage protocol (MHP) but...
REVIEW by:
E. Adams

Published: Aug 2019

Porter SB, White LJ, Osagiede O, Robards CB, Spaulding AC

Tranexamic acid administration is not associated with an increase in complications in high-risk patients undergoing primary total knee or total hip arthroplasty: a retrospective case-control study of 38,220 patients.
J Arthroplasty 2019; Aug 17 [Epub ahead of print].

#

NATA REVIEW:
This study was designed to examine whether tranexamic acid, which is a well-established therapy to reduce postoperative...
REVIEW by:
M. T. Prochaska

Published: Aug 2019

Chaudhury P, Gadre S, Schneider E, et al.

Impact of multidisciplinary pulmonary embolism response team availability on management and outcomes.
Am J Cardiol 2019; Aug 7 [Epub ahead of print].

#

NATA REVIEW:
Chaudhury et al. retrospectively analysed the outcomes of 769 consecutive adult patients with pulmonary...
REVIEW by:
J. M. Cholette

Published: Aug 2019

Douketis JD, Spyropoulos AC, Duncan J, et al.

Perioperative management of patients with atrial fibrillation receiving a direct oral anticoagulant.
JAMA Intern Med 2019; Aug 5 [Epub ahead of print].

#

NATA REVIEW:
The Perioperative Anticoagulation Use for Surgery Evaluation (PAUSE) cohort study enrolled 3007 atrial fibrillation...
REVIEW by:
C.-M. Samama

Published: Aug 2019

Zeeshan M, Hamidi M, Feinstein AJ, et al.

4-factor prothrombin complex concentrate is associated with improved survival in trauma related hemorrhage: a nationwide propensity matched analysis.
J Trauma Acute Care Surg 2019;87:274-281.

#

NATA REVIEW:
The authors conducted a retrospective study to evaluate outcomes of severely injured trauma patients who received...
REVIEW by:
J.-F. Hardy

Published: Aug 2019

McNamara H, Kenyon C, Smith R, Mallaiah S, Barclay P

Four years' experience of a ROTEM((R))-guided algorithm for treatment of coagulopathy in obstetric haemorrhage.
Anaesthesia 2019;74:984-991.

#

NATA REVIEW:
This important study by McNamara et al. reports on four years of observational data from a large UK...
REVIEW by:
B. Froessler

Published: Jul 2019

Butler EK, Mills BM, Arbabi S, et al.

Association of blood component ratios with 24-hour mortality in injured children receiving massive transfusion.
Crit Care Med 2019;47:975-983.

#

NATA REVIEW:
While the incidence of paediatric trauma requiring massive transfusion is lower than the incidence in adults,...
REVIEW by:
D. Faraoni

Published: May 2019

Bhatt DL, Pollack CV, Weitz JI, et al.

Antibody-based ticagrelor reversal agent in healthy volunteers.
N Engl J Med 2019;308:1825-1833.

#

NATA REVIEW:
Dual antiplatelet therapy (DAPT) is frequently used in patients with acute coronary syndrome, coronary stents,...
REVIEW by:
D. Faraoni

Published: May 2019

Habbab LM, Hussain S, Power P, et al.

Decreasing Postoperative Blood Loss by Topical vs. Intravenous Tranexamic Acid in Open Cardiac Surgery (DEPOSITION) study: Results of a pilot study.
J Card Surg 2019;34:305-311.

#

NATA REVIEW:
The authors performed a pilot study comparing topical versus intravenous administration of tranexamic acid. Given...
REVIEW by:
H. B. Ravn

Pages