From the Literature

Published: Nov 2019

CRASH-3 trial collaborators

Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial.
Lancet 2019;394:1713-1723.

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NATA REVIEW:
Tranexamic acid administered within 3 hours of injury in patients with head trauma reduces death. I...
REVIEW by:
B. H. Hunt

Published: Nov 2019

Harenberg J, Beyer-Westendorf J, Crowther M, et al.

Accuracy of a rapid diagnostic test for the presence of direct oral factor Xa or thrombin inhibitors in urine – a multicenter trial.
Thromb Haemost 2019; Nov 8 [Epub ahead of print].

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NATA REVIEW:
Harenberg et al. have developped a rapid colorimetric point-of-care test using patient urine sample...
REVIEW by:
C.-M. Samama

Published: Nov 2019

Bonnet A, Gilquin N, Steer N, et al.

The use of a thromboelastometry-based algorithm reduces the need for blood product transfusion during orthotopic liver transplantation: A randomised controlled study.
Eur J Anaesthesiol 2019;36:825-833.

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NATA REVIEW:
Orthotopic liver transplants have come a long way over the past several decades. While we have solved a myriad...
REVIEW by:
E. Adams

Published: Nov 2019

Chaudhury P, Gadre S, Schneider E, et al.

Impact of multidisciplinary pulmonary embolism response team availability on management and outcomes.
Am J Cardiol 2019;124:1465-1469

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NATA REVIEW:
Chaudhury et al. retrospectively analysed the outcomes of 769 consecutive adult patients with pulmonary...
REVIEW by:
J. M. Cholette

Published: Nov 2019

Raphael J, Mazer CD, Subramani S, et al.

Society of Cardiovascular Anesthesiologists clinical practice improvement advisory for management of perioperative bleeding and hemostasis in cardiac surgery patients.
J Cardiothorac Vasc Anesth 2019;33:2887-2899.

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NATA REVIEW:
Bleeding after cardiac surgery is a common and serious complication leading to transfusion of multiple blood...
REVIEW by:
J. M. Cholette

Published: Oct 2019

Roy A, Stanford S, Nunn S, et al.

Efficacy of fibrinogen concentrate in major abdominal surgery – a prospective, randomized, controlled study in cytoreductive surgery for pseudomyxoma peritonei.
J Thromb Haemost 2019; Oct 26 [Epub ahead of print].

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NATA REVIEW:
This European single-centre trial randomised patients undergoing cytoreductive surgery with hyperthermic intraperitoneal...
REVIEW by:
J. H. Levy

Published: Oct 2019

Callum J, Farkouh ME, Scales DC, et al.

Effect of fibrinogen concentrate vs cryoprecipitate on blood component transfusion after cardiac surgery: The FIBRES randomized clinical trial.
JAMA 2019; Oct 21 [Epub ahead of print].

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NATA REVIEW:
Hypofibrinogenaemia is frequently observed in bleeding patients after cardiac surgery with cardiopulmonary bypass....
REVIEW by:
D. Faraoni

Published: Sep 2019

Paciullo F, Bury L, Noris P, et al.

Antithrombotic prophylaxis for surgery-associated venous thromboembolism risk in patients with inherited platelet disorders. The SPATA-DVT Study.
Haematologica 2019; Sep 26 [Epub ahead of print].

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NATA REVIEW:
This is a retrospective study of patients with inherited platelet disorders undergoing surgical procedures. No...
REVIEW by:
B. H. Hunt

Published: Sep 2019

Nellis ME, Tucci M, Lacroix J, et al.

Bleeding Assessment Scale in Critically Ill Children (BASIC): physician-driven diagnostic criteria for bleeding severity.
Crit Care Med 2019; Sep 25 [Epub ahead of print].

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NATA REVIEW:
This is the first ever bleeding assessment scale developed for the evaluation of bleeding in critically ill children....
REVIEW by:
E. Adams

Published: Sep 2019

Roquet F, Neuschwander A, Hamada S, et al.

Association of early, high plasma-to-red blood cell transfusion ratio with mortality in adults with severe bleeding after trauma.
JAMA Netw Open 2019;2:e1912076.

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NATA REVIEW:
Roquet et al. report the results of a large retrospective trauma registry study on optimal FFP to RBC...
REVIEW by:
A. P. J. Vlaar

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