From the Literature

Published: Jul 2016

Barillari G, Londero AP, Brenner B, et al.

Recurrence of venous thromboembolism in patients with recent gestational deep vein thrombosis or pulmonary embolism: Findings from the RIETE Registry.
Eur J Intern Med 2016;32:53-59.

#

NATA REVIEW:
This paper looks at the recurrent VTE rate in women who had VTE during pregnancy. As with all data from observational...
REVIEW by:
B. J. Hunt

Published: Jun 2016

Baharoglu MI, Cordonnier C, Salman RA, et al.

Platelet transfusion versus standard care after acute stroke due to spontaneous cerebral haemorrhage associated with antiplatelet therapy (PATCH): a randomised, open-label, phase 3 trial.
Lancet 2016;387:2605-2613.

#

NATA REVIEW:
Essential reading for all. A reminder that however logical a therapy might be (giving platelets to those with...
REVIEW by:
B. J. Hunt

Published: Jun 2016

Larsen TB, Skjøth F, Nielsen PB, Kjældgaard JN, Lip GY

Comparative effectiveness and safety of non-vitamin K antagonist oral anticoagulants and warfarin in patients with atrial fibrillation: propensity weighted nationwide cohort study.
BMJ 2016;353:i3189.

#

NATA REVIEW:
Another article providing real-world data on DOACs compared with warfarin. Helpful also in comparing efficacy...
REVIEW by:
B. J. Hunt

Published: Jun 2016

Gonzalez E, Moore EE, Moore HB, et al.

Goal-directed hemostatic resuscitation of trauma-induced coagulopathy: a pragmatic randomized clinical trial comparing a viscoelastic assay to conventional coagulation assays.
Ann Surg 2016;263:1051-1059.

#

NATA REVIEW:
In a pragmatic RCT, Gonzalez and colleagues from Denver, CO, USA, show that resuscitation guided by a viscoelastic...
REVIEW by:
J. Stensballe

Published: May 2016

Wafaisade A, Lefering R, Bouillon B, Böhmer AB, Gässler M, Ruppert M

Prehospital administration of tranexamic acid in trauma patients.
Crit Care 2016;20:143.

#

NATA REVIEW:
In this retrospective study, Wafaisade et al. investigated the effect of prehospital administration...
REVIEW by:
S. R. Ostrowski

Published: Feb 2016

Myles PS, Smith JA, Forbes A, et al.

Stopping vs. continuing aspirin before coronary artery surgery.
N Engl J Med 2016;374:728-737.

#

NATA REVIEW:
Myles et al. have used a 2-by-2 factorial trial design to randomly assign patients who were scheduled...
REVIEW by:
C.-M. Samama

Published: Jan 2016

Majeed A, Goldhaber SZ, Kakkar A, et al.

Bleeding events with dabigatran or warfarin in patients with venous thromboembolism.
Thromb Haemost 2016;115:291-298.

#

NATA REVIEW:
Since the approval of dabigatran for stroke prevention in non-valvular atrial fibrillation and for the treatment...
REVIEW by:
F. Bonhomme

Published: Dec 2015

Siegal DM, Curnutte JT, Connolly SJ, et al.

Andexanet alfa for the reversal of factor Xa inhibitor activity.
N Engl J Med 2015;373:2413-2424

#

NATA REVIEW:
The direct factor Xa inhibitors apixaban and rivaroxaban are increasingly used for the prevention and the...
REVIEW by:
D. Faraoni

Published: Nov 2015

Refaai MA, Goldstein JN, Lee ML, Durn BL, Milling TJ, Jr., Sarode R

Increased risk of volume overload with plasma compared with four-factor prothrombin complex concentrate for urgent vitamin K antagonist reversal.
Transfusion 2015;55:2722-2729.

#

NATA REVIEW:
Immediate reversal of the anticoagulant effect of vitamin K antagonists can be achieved by administration of...
REVIEW by:
M. Levi

Published: Sep 2015

Eerenberg ES, Middeldorp S, Levi M, Lensing AW, Buller HR

Clinical impact and course of major bleeding with rivaroxaban and vitamin K antagonists.
J Thromb Haemost 2015;13:1590-1596.

#

NATA REVIEW:
Non-vitamin K oral anticoagulants (NOACs) are increasingly replacing standard vitamin K antagonists (VKAs) and/or...
REVIEW by:
D. Faraoni

Pages