From the Literature

Published: May 2015

Gross I, Seifert B, Hofmann A, Spahn DR

Patient blood management in cardiac surgery results in fewer transfusions and better outcome.
Transfusion 2015;55:1075-1081.

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NATA REVIEW:
Gross et al. compared transfusion and clinical data between the period prior to implementing patient...
REVIEW by:
J.-F. Hardy

Published: Apr 2015

Sentilhes L, Lasocki S, Ducloy-Bouthors AS, et al.

Tranexamic acid for the prevention and treatment of postpartum haemorrhage.
Br J Anaesth 2015;114:576-587.

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NATA REVIEW:
This systematic review provides a good summary of trials evaluating tranexamic acid (TXA) for the prevention...
REVIEW by:
B. J. Hunt

Published: Mar 2015

Shields LE, Wiesner S, Fulton J, Pelletreau B

Comprehensive maternal hemorrhage protocols reduce the use of blood products and improve patient safety.
Am J Obstet Gynecol 2015;212:272-280.

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NATA REVIEW:
This was a paper that I really enjoyed reviewing. It discusses the effect of applying a comprehensive protocol...
REVIEW by:
B. J. Hunt

Published: Mar 2015

Fraser IS, Mansour D, Breymann C, Hoffman C, Mezzacasa A, Petraglia F

Prevalence of heavy menstrual bleeding and experiences of affected women in a European patient survey.
Int J Gynaecol Obstet 2015;128:196-200.

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NATA REVIEW:
The authors conducted an internet-based survey to examine the prevalence of heavy menstrual bleeding (HMB) among...
REVIEW by:
L. T. Goodnough

Published: Mar 2015

Karkouti K, McCluskey SA, Callum J, et al.

Evaluation of a novel transfusion algorithm employing point-of-care coagulation assays in cardiac surgery: a retrospective cohort study with interrupted time-series analysis.
Anesthesiology 2015;122:560-570.

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NATA REVIEW:
The authors evaluated a novel transfusion algorithm that uses point-of-care coagulation testing. They enrolled...
REVIEW by:
J.-F. Hardy

Published: Feb 2015

Practice guidelines for perioperative blood management: an updated report by the American Society of Anesthesiologists Task Force on Perioperative Blood Management.
Anesthesiology 2015;122:241-275.

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NATA REVIEW:
These Practice Guidelines update “Practice Guidelines for Perioperative Blood Transfusion and Adjuvant Therapies:...
REVIEW by:
J.-F. Hardy

Published: Feb 2015

Herzog E, Kaspereit F, Krege W, et al.

Effective reversal of edoxaban-associated bleeding with four-factor prothrombin complex concentrate in a rabbit model of acute hemorrhage.
Anesthesiology 2015;122:387-398.

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NATA REVIEW:
New-generation oral anticoagulants, specifically targeted at thrombin or factor Xa, have been shown to be effective...
REVIEW by:
M. Levi

Published: Feb 2015

Hoffman M, Volovyk Z, Monroe DM

Reversal of dabigatran effects in models of thrombin generation and hemostasis by factor VIIa and prothrombin complex concentrate.
Anesthesiology 2015;122:353-362.

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NATA REVIEW:
Dabigatran is a direct thrombin inhibitor increasingly used for the prevention and treatment of thromboembolism....
REVIEW by:
D. Faraoni

Published: Feb 2015

Bouet PE, Ruiz V, Legendre G, Gillard P, Descamps P, Sentilhes L

High-dose tranexamic acid for treating postpartum haemorrhage after vaginal delivery.
Br J Anaesth 2015;114:339-341.

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NATA REVIEW:
This report describes 60 women given high-dose tranexamic acid (4 g) if they sustained >800 mL...
REVIEW by:
B. J. Hunt

Published: Feb 2015

Reed GW, Kumar A, Guo J, et al.

Point-of-care platelet function testing predicts bleeding in patients exposed to clopidogrel undergoing coronary artery bypass grafting: Verify Pre-Op TIMI 45 – a pilot study.
Clin Cardiol 2015;38:92-98.

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NATA REVIEW:
The authors performed a proof-of-principle pilot study indicating that point-of-care platelet function testing...
REVIEW by:
S. Kozek-Langenecker

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