From the Literature

Published: Oct 2014

Vonk AB, Meesters MI, van Dijk WB, et al.

Ten-year patterns in blood product utilization during cardiothoracic surgery with cardiopulmonary bypass in a tertiary hospital.
Transfusion 2014;54:2608-2616.

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NATA REVIEW:
Vonk et al. describe the blood-conservation strategies and the overall consumption of red blood cells...
REVIEW by:
J.-F. Hardy

Published: Oct 2014

Frank SM, Wick EC, Dezern AE, et al.

Risk-adjusted clinical outcomes in patients enrolled in a bloodless program.
Transfusion 2014;54:2668-2677.

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NATA REVIEW:
This is a very interesting retrospective, risk-adjusted, clinical outcome study examining the application of...
REVIEW by:
C. Vagianos

Published: Oct 2014

Du Y, Xu J, Wang G, et al.

Comparison of two tranexamic acid dose regimens in patients undergoing cardiac valve surgery.
J Cardiothorac Vasc Anesth 2014;28:1233-1237.

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NATA REVIEW:
Du et al. report on a randomised trial evaluating low-dose versus high-dose tranexamic acid during cardiac...
REVIEW by:
J. Stensballe

Published: Oct 2014

Welsh KJ, Padilla A, Dasgupta A, Nguyen AN, Wahed A

Thromboelastography is a suboptimal test for determination of the underlying cause of bleeding associated with cardiopulmonary bypass and may not predict a hypercoagulable state.
Am J Clin Pathol 2014;142:492-497.

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NATA REVIEW:
Welsh and colleagues investigated thrombelastography (TEG) and conventional coagulation tests (CCT) in 67 retrospectively...
REVIEW by:
J. Stensballe

Published: Oct 2014

Adelmann D, Klaus DA, Illievich UM, et al.

Fibrinogen but not factor XIII deficiency is associated with bleeding after craniotomy.
Br J Anaesth 2014;113:628-633.

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NATA REVIEW:
Effective haemostasis in case of haemorrhage requires fibrinogen activation to form a haemostatic fibrin clot...
REVIEW by:
O. Habler

Published: Oct 2014

Galas FR, de Almeida JP, Fukushima JT, et al.

Hemostatic effects of fibrinogen concentrate compared with cryoprecipitate in children after cardiac surgery: A randomized pilot trial.
J Thorac Cardiovasc Surg 2014;148:1647-1655.

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NATA REVIEW:
Children undergoing cardiac surgery are at increased risk for perioperative bleeding and allogeneic blood product...
REVIEW by:
D. Faraoni

Published: Oct 2014

Kasivisvanathan R, Abbassi-Ghadi N, Kumar S, et al.

Risk of bleeding and adverse outcomes predicted by thromboelastography platelet mapping in patients taking clopidogrel within 7 days of non-cardiac surgery.
Br J Surg 2014;101:1383-1390.

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NATA REVIEW:
Kasivisvanathan and colleagues open the door a little further to tailored antiplatelet therapy, showing good...
REVIEW by:
J. Stensballe

Published: Oct 2014

Adelmann D, Wiegele M, Wohlgemuth RK, et al.

Measuring the activity of apixaban and rivaroxaban with rotational thrombelastometry.
Thromb Res 2014;134:918-923.

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NATA REVIEW:
Although no routine coagulation monitoring is recommended during treatment with direct factor Xa inhibitors,...
REVIEW by:
D. Faraoni

Published: Sep 2014

Collins PW, Lilley G, Bruynseels D, et al.

Fibrin-based clot formation as an early and rapid biomarker for progression of postpartum hemorrhage: a prospective study.
Blood 2014;124:1727-1736.

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NATA REVIEW:
In a prospective, observational study, an interdisciplinary group of authors found FIBTEM to predict progression...
REVIEW by:
S. Kozek-Langenecker

Published: Sep 2014

Dutton RP, Lee LA, Stephens LS, Posner KL, Davies JM, Domino KB

Massive hemorrhage: a report from the Anesthesia Closed Claims Project.
Anesthesiology 2014;121:450-458.

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NATA REVIEW:
Dutton and colleagues reviewed 3,211 closed surgical or obstetric anaesthesia malpractice claims related to haemorrhage...
REVIEW by:
P. Johansson

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