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Hypotensive transfusion reactions can occur with blood products that are leukoreduced before storage.

The authors describe hypotensive transfusion reactions in 2 patients taking ACE inhibitors, in one case corresponding to the transfusion of leukodepleted autologous whole blood, and in the other with non-leukodepleted whole blood of acute normovolemic hemodilution. In both cases severe impairment of des-Arg-bradykinin could be demonstrated. The authors conclude that not only bedside filtration but […]

Patient safety and blood transfusion: new solutions.

Interesting paper on new solutions for making transfusions safer. The only aspect which is missing is a better education of the staff involved in hemotherapy, which is even more important than monitoring, etc. – Volker Kretschmer