Heparin-level-based anticoagulation management during cardiopulmonary bypass: a pilot investigation on the effects of a half-dose aprotinin protocol on postoperative blood loss and hemostatic activation and inflammatory response.
Koster et al describe the use of a half-dose aprotinin protocol and the influence on postoperative blood loss. The second endpoint of this investigation was a bunch of several hemostatic […]
Anemia in the intensive care unit.
Somewhat superficial overview about anaemia in intensive care patients whithout new aspects.>br> – Volker Kretschmer
The in vitro effects of crystalloids and colloids on coagulation.
Worth a close look for those with a specialist interest in this area. Adds to a fast growing body of literature on the various effects of i.v. solutions on coagulation […]
Successful use of recombinant activated factor VII for trauma-associated hemorrhage in a patient without preexisting coagulopathy.
This is a detailed first case report in the United States on using recombinant activated factor VIIa in treating massive uncontrollable bleeding following stab wound trauma to the liver in […]
Aprotinin in orthotopic liver transplantation: Evidence for a prohemostatic, but not a prothrombotic, effect.
This study supports the hypothesis that aprotinin is an anticoagulant which prolongs the aPTT and has no or marginal risks of thromboembolic complications. – Wulf Dietrich.
Development of an animal model for assessment of the hemostatic efficacy of fibrin sealant in vascular surgery.
Having a sound and reproducible animal model to test the value of an existing therapy beyond its initial application is certainly a step forward. Kheirabadi and associates have taken this […]
Blood loss in elective coronary artery surgery: A comparison of centrifugal versus roller pump heads during cardiopulmonary bypass.
In an age of widespread use of anticogulants and patelet inhibitors for cardiac surgery, it is important to know the impact on bleeding and coagulation for every componants of the […]
Comparison between 1-hour and 24-hour drain clamping using diluted epinephrine solution after total knee arthroplasty.
Another paper concerning the use of drains in total knee arthroplasty. Not a large number of cases, but interesting comments on the ongoing controversy, i. e., Should drains be used […]