Effect of blood transfusion on long-term survival after cardiac operation.

The authors studied a database of 1,915 patients who underwent isolated first time myocardial revascularization between 1994 and 1997 and found that blood transfusions during or after coronary artery bypass operations were associated with increased long-term mortality (risk ratio = 1.7; 95% confidence interval = 1.4 to 2.0). This retrospective database analysis is important and […]

Intraoperative cell salvage in radical retropubic prostatectomy.

This article attempts a risk evaluation with only 62 patients. Unfortunately, statistics tell us that, even to show a risk increase (e.g., of metastasis) by as much as 10%, one needs more than 1000 patients (Harrison et al., Br J Surg 1992;79:355-357)! In terms of transfusion risks, a level of sensitivity of 10% is out […]