Does priming implementation with low-dose albumin reduce postoperative bleeding following cardiopulmonary bypass?
Concludes that addition of Albumin to crystalloid prime reduces bleeding following cardiac by-pass surgery. At first glance looks like a big study (n=154 with crystalloid and low dose 20% albumin […]
Autologous blood sequestration using a double venous reservoir bypass circuit and polymerized hemoglobin prime.
This experimental study describes a modified cardiopulmonary bypass circuit using a bovine hemoglobin solution priming that protects a portion of the autologous blood volume from the damaging effects of bypass. […]
Recombinant human transgenic antithrombin in cardiac surgery: a dose-finding study.
This is a very important paper in two ways. First, it highlights ongoing activation of hemostasis in the postoperative period as demonstrated by the control group. The scale of Figure […]
Transfusion in premature infants impairs production and/or release of red blood cells, white blood cells and platelets.
The author concludes that suppression of erythro-, leuko- and thrombopoiesis within 48 hours after transfusion decreases the amount of precursor cells in the peripheral blood. This is a very important […]
Detection and removal of fat particles from postoperative salvaged blood in orthopedic surgery.
The authors describe a new and interesting method for the detection of fat droplets in blood. The topic itself and the problem of fat in salvaged orthopedic wound blood is […]
Absence of beneficial effect of acute normovolemic hemodilution combined with aprotinin on allogeneic blood transfusion requirements in cardiac surgery.
This prospective randomized study showed that acute normovolemic hemodilution (ANH) did not reduce the risk of allogeneic blood transfusion in elective cardiac surgical patients. However, the interpretation of these results […]
Are lactated Ringer’s solution and normal saline solution equal with regard to coagulation?
This study compares the perioperative effects of a saline crystalloid and a more balanced and buffered electrolyte crystalloid on clotting. The differences thought to be related to blood clotting that […]
Clinical application of vacuum-assisted cardiopulmonary bypass with a pressure relief valve.
Hayashi and colleagues have studied the value of a vacuum-assisted cardiopulmonary bypass system in simplifying bypass while reducing the volume of fluid needed for pump priming. They were successful in […]
Heparin coating of the extracorporeal circuit combined with leukocyte filtration reduces coagulation activity, blood loss and blood product substitution.
Heparin bonded circuits have become standard in extracorporeal bypass circuits for open heart surgery. Leukoreduction of allogeneic red blood cells is also considered a standard of care in many countries. […]
Blood loss in elective coronary artery surgery: A comparison of centrifugal versus roller pump heads during cardiopulmonary bypass.
In an age of widespread use of anticogulants and patelet inhibitors for cardiac surgery, it is important to know the impact on bleeding and coagulation for every componants of the […]
Influence of a new hydroxyethylstarch preparation (HES 130/ 0.4) on coagulation in cardiac surgical patients.
Note that volumes of Gelatine and Starch required to maintain CVP are no different between two groups, suggesting that the two solutions are equally effective as plasma volume expanders. However, […]
Coronary artery bypass grafting surgery without the routine application of blood products: is it feasible?
The results of this study are rather surprising. The control group receiving FFP required significantly more red cell concentrates (RBCs). One of the reasons explaining this could be that the […]