This is one of the largest PRCTs of colloid vs. colloid to date. It forms the basis of the new European dose limit for HES 130/0.4 at 50 mL/kg. Trials […]
Worth a close look for those with a specialist interest in this area. Adds to a fast growing body of literature on the various effects of i.v. solutions on coagulation […]
This is a case report of two female patients with severe vaginal bleeding following previous treatment of gynecological malignancies and no pre-existing coagulation factor deficiency. Bleeding was controlled with two […]
Uncontrolled bleeding remains a major problem in intensive care and emergency medicine which still requires effective and innovative treatment options. This editorial highlights that there is growing evidence on the […]
This is another case report on the efficacy of Novoseven in controlling severe bleeding in cardiac surgery. Post-operative bleeding continued in spite of the use of blood products and aprotinin […]
This is an interesting case report on the use of rFVIIa in treating uncontrollable surgical bleeding in a patient not known to have a pre-existing coagulopathy. The patient had a […]
This is an interesting work showing the efficacy of rFVIIa in controlling post traumatic hemorrhage in an animal model, especially after the publication of several case reports of the effective […]
Note: See also the useful invited commentary by John A. Elefteriades on pages 743-4. – F. Regan and M. Contreras.
Etiology of bleeding in cirrhotic patients during surgery is multifactorial, and its management includes several measures such as replacement of coagulation factors and platelets as well as the use of […]
This is a very interesting article which casts new light on the mechanism of hemostasis of rFVIIa in hemophiliac patients with inhibitors to factor VIII. rFVIIa is known to exert […]
This article starts with a general overview on mechanism of action, uses and safety of rFVIIa as well as the hemostatic disorders which are associated with liver disease. It states […]
This study supports the hypothesis that aprotinin is an anticoagulant which prolongs the aPTT and has no or marginal risks of thromboembolic complications. – Wulf Dietrich.
This is a new open-label study, which showed efficacy of rFVIIa in normalising prothrombin time and effective control of bleeding esophageal varices in cirrhotic patients, in addition to safety in […]
This is a double-blind placebo controlled dose escalation trial evaluating efficacy and safety of inactivated rFVIIa (FFR-rFVIIa) as an antithrombotic agent. The trial showed a dose dependent prolongation of the […]
This article is of interest in clinical decision-making related to starches usage. However, its interest is even higher for researchers in the field of volume replacement. – M. Mythen.
NATA: Network for the advancement of Patient Blood Management, Haemostasis and Thrombosis
MISSION: Providing a multidisciplinary forum for dialogue between haematologists, transfusion medicine specialists, anaesthesiologists, intensive care and emergency physicians, surgeons, perfusionists, nurses, biomedical scientists and ther healthcare professionals.
I am text block. Click edit button to change this text. Lorem ipsum dolor sit amet, consectetur adipiscing elit. Ut elit tellus, luctus nec ullamcorper mattis, pulvinar dapibus leo.