A comparison of albumin and saline for fluid resuscitation in the intensive care unit.
Essential reading material. The largest PRCT of Albumin vs Saline in 7,000 critically ill patients in Australia and New Zealand. Concludes “no-difference” in 28 day mortality. Subset trends to excess […]
Use of perflubron emulsion to decrease allogeneic blood transfusion in high-blood-loss non-cardiac surgery: results of a European phase 3 study.
The authors should be commended for carrying out an elaborate multicenter study in such an elegant fashion. The Methods are well described, the statistics appropriate and the Results are presented […]
Intravascular volume replacement therapy with synthetic colloids: is there an influence on renal function?
A good summary of the literature on this frequently asked question. Some excellent tables and a useful citation listing. The important take home message is sadly all too familiar: inadequate […]
The influence of crystalloid and colloid replacement solutions in acute normovolemic hemodilution: a preliminary survey of hemostatic markers.
This prospective randomized single blinded study nicely showed the dual effects of plasma substitutes used in acute normovolemic hemodilution. Solutions that have an impact on hemostasis like dextran and high […]
Intraoperative colloid administration reduces postoperative nausea and vomiting and improves postoperative outcomes compared with crystalloid administration.
An important and long awaited addition to the colloid vs crystalloid debate. A blinded, adequately powered PRCT that asks a sensible, hypothesis driven question, i.e., Is there a difference in […]