The use of rFVIIa in conditions associated with disseminated intravascular coagulation (DIC) has always been an area of concern in view of the theoretical possibility of enhancing thrombotic complications. However, […]
The recommended measures to reduce the use of blood transfusions are certainly right and one can recommend to follow the proposals. However, the excellent results of small trials investigated by […]
This is an interesting report on a small series of children with inherited platelet dysfunction treated with rFVIIa for acute bleeding or preoperatively. Response seemed to correlate with type of […]
The role of rFVIIa in improving hemostasis in patients with chronic liver disease and/or thrombocytopenia has been reported in many case reports. This article is reporting a 59 yr old […]
This paper reviews the current trials for the extended use of rFVIIa outside hemophilia patients with inhibitors. These areas include thrombocytopenia, liver disease, trauma, intracerebral hemorrhage, surgery, and anticoagulation. – […]
This is another case report on the efficacy of Novoseven in controlling severe bleeding in cardiac surgery. Post-operative bleeding continued in spite of the use of blood products and aprotinin […]
This is an interesting work showing the efficacy of rFVIIa in controlling post traumatic hemorrhage in an animal model, especially after the publication of several case reports of the effective […]
An excellent study about the use of AT III in septic patients. Carefully conducted study: the description in the method section is outstanding. It is noteworthy that this is the […]
This is a relatively new area for using rFVIIa, which is to treat uncontrolled haemorrhage in patients with severe trauma, following the earlier report of using rFVIIa successfully in treating […]
This is a new open-label study, which showed efficacy of rFVIIa in normalising prothrombin time and effective control of bleeding esophageal varices in cirrhotic patients, in addition to safety in […]
A good overall review on the characterization, mechanism of action, and preclinical and current clinical evidence for the efficacy and safety of rFVIIa. – M. Aldouri.
NATA: Network for the advancement of Patient Blood Management, Haemostasis and Thrombosis
MISSION: Providing a multidisciplinary forum for dialogue between haematologists, transfusion medicine specialists, anaesthesiologists, intensive care and emergency physicians, surgeons, perfusionists, nurses, biomedical scientists and ther heathcare professionals.
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