Possible role of recombinant activated factor VII (RFVIIa) in the control of hemorrhage associated with massive trauma.
This is a report on the largest series on the use of rFVIIa in treating patients suffering from uncontrolled bleeding as a result of trauma in spite of surgical treatment […]
Recombinant activated factor VII: its mechanism of action and role in the control of hemorrhage.
This is an overview on the mechanism of action of rFVIIa and its role in hemostasis. rFVIIa directly activates FX, increases thrombin activation on activated platelets, and leads to generation […]
The effect of recombinant factor VIIa on coagulopathic pigs with grade V liver injuries.
This study illustrates one of the unusual situations in Medicine where evidence of drug efficacy in human preceded animal studies. After the publication of several case reports on the effectiveness […]
Recombinant activated factor VII for adjunctive hemorrhage control in trauma.
This is a relatively new area for using rFVIIa, which is to treat uncontrolled haemorrhage in patients with severe trauma, following the earlier report of using rFVIIa successfully in treating […]