Discussion of very recent literature, calculation of current risk of transfusion transmitted viral infections after introduction of NAT-HCV and NAT-HIV. Determination of cost/benefit of introduction of NAT. Conclusive statement that p24 antigen testing should be omitted after introducztion of NAT. – Volker Kretschmer
A novel hemostatic agent: the potential role of recombinant activated factor VII (RFVIIa) in anesthetic practice.
This is an excellent literature review on the adjuvant use of rFVIIa in treating severe bleeding associated with surgical procedures in non-hemophiliac patients. It gives an overview of the mechanism of action of rFVIIa and its efficacy in patients with hemophilia, platelet dysfunction and liver disease. It also reviews its efficacy in managing bleeding in […]
The article demonstrates that the decision towards autologous blood donation (ABD) does not, in the majority of cases, depend on the hemoglobin values but on additional health risk factors. There was even an increase of ABD from 1995/96 to 1998/99, which was not the case, for example, in Europe. Otherwise, the data confirm the generally […]
Autologous transfusion of shed mediastinal blood after coronary artery bypass grafting and bacterial contamination.
A good article to read. Many physicians retransfuse unwashed blood, but most experts prefer washed blood in all cases. – H. Gombotz.
Amplification of the DNA polymerase I gene of Treponema pallidum from whole blood of persons with syphilis.
The article confirms by means of the sensitive PCR technique that Treponema pallidum may be found in blood during the whole course of syphilis infection. – V. Kretschmer.
The article gives a good overview about incidence, pathogenesis, clinical symptoms, clinical course, diagnostics, therapy and prognosis of fetal parvovirus B19 infection by analysis of literature. The prognosis is mainly determined by the anemia. Data suggest a benefit of transfusion therapy. – V. Kretschmer.
The article is also showing, what is already known, that TTV is transmitted by blood and transplants but that no pathogenicity of the virus could be proven yet. – V. Kretschmer.