Successful use of recombinant factor VIIa in a patient with inhibitor secondary to severe factor XI deficiency.
After using rFVIIa effectively in the treatment of hemophilia patients with inhibitors against factors VIII and IX, this case report illustrates its efficacy in treating a 62-year-old woman with high […]
Case report on recombinant coagulation factor VIIa in the treatment of three haemophilia A patients with inhibitors in Singapore.
This is a first case report on using rFVIIa (Novoseven) to treat hemophilia patients with high response inhibitors to factor VIII in Singapore. The patients had bleeding with moderate severity, […]
Efficacy of a low-dose intravenous iron sucrose regimen in peritoneal dialysis patients.
The authors evaluated a low dose iron substitution scheme for the effectiveness in patients with peritoneal dialysis: 50 mg iron sucrose every other week is effective in patients with ferritin […]
Effective hemostasis with rFVIIa treatment in two patients with severe thrombocytopenia and life-threatening hemorrhage.
This article reports 2 patients with severe thrombocytopenia and severe hemorrhage which did not respond to standard therapy and platelet transfusion, but responded quickly to administration of a single dose […]
Clinical significance of RBC alloantibodies and autoantibodies in sickle cell patients who received transfusions.
The study shows that transfusion of blood matched for Rh and Kell systems would reduce alloimmunization to 27% and reduce delayed hemolytic transfusion reaction, but would not prevent it. Delayed […]
Reduction in erythropoietin doses by the use of chronic intravenous iron supplementation in iron-replete hemodialysis patients.
The authors from Taiwan state that they used “Ferrum Hausmann, a ferric polymaltose complex.” Under the same name (Ferrum Hausmann), iron saccharate (identical to iron sucrose) has been licensed in […]
Successful use of recombinant activated factor VII for trauma-associated hemorrhage in a patient without preexisting coagulopathy.
This is a detailed first case report in the United States on using recombinant activated factor VIIa in treating massive uncontrollable bleeding following stab wound trauma to the liver in […]
Outcome of infants receiving in-utero transfusions for haemolytic disease.
Retrospective analysis of infants receiving in-utero transfusion showing good outcome. No information about immunohematological methods used. There was a trend of less exchange transfusions in infants having more in-utero transfusions. […]
Prospective RBC phenotype matching in a stroke-prevention trial in sickle cell anemia: a multicenter transfusion trial.
For a transfusionist from West/North Europe, the results are predictable and the conclusion expectable. In Germany, the prospective RBC phenotype matching in sickle cell anemia and thalassemia, and even in […]
Off-label use of recombinant factor VIIa in patients following bone marrow transplantation.
This is a report on off-label extended use of rFVIIa in managing pulmonary, vesical and GI haemorrhage in 3 patients post-BMT, who failed to respond to blood component transfusion and […]
Liver resections with or without pedicle clamping.
The authors demonstrate in a well-thought-out study what we have all suspected based on trauma experience: that temporary clamping of the hepatic pedicle, or the Pringle manouver, can reduce blood […]