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Intraoperative colloid administration reduces postoperative nausea and vomiting and improves postoperative outcomes compared with crystalloid administration.

An important and long awaited addition to the colloid vs crystalloid debate. A blinded, adequately powered PRCT that asks a sensible, hypothesis driven question, i.e., Is there a difference in edema related postoperative complications when colloids are compared to crystalloids? Essential reading for anyone planning a study in this area. Perhaps uneasy reading for the […]

HBOC-201 improves survival in a swine model of hemorrhagic shock and liver injury.

This experimental study highlights the potential beneficial therapeutic effect of a hemoglobin-based oxygen carrier (HBOC) used as a resuscitation fluid during severe traumatic shock. In contrast to colloid (high molecular weight hydroxyethyl starch) based resuscitation, a similar volume of HBOC from bovine origin prevented exsanguination cardiac arrest, allowing for significantly higher long term (96 hr) […]