Recombinant human hemoglobin with reduced nitric oxide-scavenging capacity restores effectively pancreatic microcirculatory disorders in hemorrhagic shock.
A recombinant hemoglobin based oxygen carrier with reduced nitric oxide-scavenging properties through site directed mutagenesis of the heme pocket has been developed. This second-generation product has been shown to be […]
Polymerized bovine hemoglobin solution as a replacement for allogeneic red blood cell transfusion after cardiac surgery: results of a randomized, double-blind trial.
The article by Jerrold Levy et al. is one of the few randomized controlled trials published on the use of hemoglobin-based oxygen-carrying (HBOC) solutions in patients. Similarly to the study […]