Use of activated recombinant coagulation factor VII in patients undergoing reconstruction surgery for traumatic fracture of pelvis or pelvis and acetabulum: a double-blind, randomized, placebo-controlled trial.
This randomized study did not show significant difference between perioperative blood loss or blood transfusion requirement by prophylactic use of rFVIIa in patients with normal hemostasis undergoing pelvic surgery. No […]
Recombinant factor VIIa for upper gastrointestinal bleeding in patients with cirrhosis: a randomized, double-blind trial.
This is a very well designed large international study which studied efficacy and safety of rFVIIa in controlling upper gastrointestinal bleeding in cirrhotic patients. Eight doses of rFVIIa or placebo […]