This paper reports the procoagulant effect of rFVIIa in experimental thrombocytopenia, and in thromboasthenic platelets due to natural or experimentally induced glycoprotein deficiency. It shows that rFVIIa improved fibrin deposition, […]
This is a clearly written article detailing the mechanism of action of rFVIIa and its interaction with tissue factor and platelets leading to its hemostatic effect in hemophilia patients with […]
This is a case report on a 31-yr-old woman who suffered with severe post-partum hemorrhage (PPH) following a cesarean section because of severe HELLP syndrome. She did not respond to […]
This is a letter to the editor describing a 50 yr old woman who presented with pancreatitis but subsequently required laparatomy for pancreatectomy, splenectomy and subtotal gastrectomy. There was profuse […]
This is a case report on treating 2 children who had uncontrolled bleeding related to spinal fusion surgery in spite of treatment with aprotinin and FFP. Bleeding was controlled with […]
This is another case report on the use of rFVIIa in controlling excessive bleeding during open heart surgery. A 57 year old woman underwent implantation of bilateral ventricular assist device […]
This is a case report on a successful use of recombinant factor VIIa in treating hematemesis in an 11-month-old infant who suffered with esophageal varices, hepatic dysfunction and previous necrotizing […]
Three cases of hemophilia A with inhibitors to factor VIII underwent total knee arthroplasty (TKA) using rFVIIa in the first patient, rFVIIa and high dose rFVIII in the second and […]
This is a case report of two female patients with severe vaginal bleeding following previous treatment of gynecological malignancies and no pre-existing coagulation factor deficiency. Bleeding was controlled with two […]
Uncontrolled bleeding remains a major problem in intensive care and emergency medicine which still requires effective and innovative treatment options. This editorial highlights that there is growing evidence on the […]
This paper reviews the current trials for the extended use of rFVIIa outside hemophilia patients with inhibitors. These areas include thrombocytopenia, liver disease, trauma, intracerebral hemorrhage, surgery, and anticoagulation. – […]
This is a case report of bleeding and prolonged APTT in a 39-yr old woman one month post-partum, due to acquired inhibitor of factor IX. The patient was successfully treated […]
This is a very good review on the use and mechanism of action of rFVIIa in acquired hemophilia. It reviews the physiological coagulation pathway and the central role of factor […]
This paper reviews the existing evidence supporting the efficacy and safety of rFVIIa in treating bleeding manifestations in patients with thrombocytopenia or those with excessive anticoagulation with warfarin. Currently this […]
This is an interesting and challenging area for the use of rFVIIa at early stages of hemorrhagic stroke in order to prevent growth of hematoma which occurs in this type […]
NATA: Network for the advancement of Patient Blood Management, Haemostasis and Thrombosis
MISSION: Providing a multidisciplinary forum for dialogue between haematologists, transfusion medicine specialists, anaesthesiologists, intensive care and emergency physicians, surgeons, perfusionists, nurses, biomedical scientists and ther healthcare professionals.
I am text block. Click edit button to change this text. Lorem ipsum dolor sit amet, consectetur adipiscing elit. Ut elit tellus, luctus nec ullamcorper mattis, pulvinar dapibus leo.