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The interaction between platelets and factor VII/VIIa.

This is a clearly written article detailing the mechanism of action of rFVIIa and its interaction with tissue factor and platelets leading to its hemostatic effect in hemophilia patients with inhibitors and those with platelet disorders. – Maadh Aldouri

Orthopaedic surgery in haemophilic patients with inhibitors: an overview.

This is an excellent review on a large series reporting the use of rFVIIa in orthopedic surgeries in patients with hemophilia A and B with inhibitors, in addition to a review of the literature. Major orthopedic procedures were carried out, as well as multiple proce-dures on the same patients were possible with very good efficacy […]