Effect of blood transfusion on long-term survival after cardiac operation.

The authors studied a database of 1,915 patients who underwent isolated first time myocardial revascularization between 1994 and 1997 and found that blood transfusions during or after coronary artery bypass operations were associated with increased long-term mortality (risk ratio = 1.7; 95% confidence interval = 1.4 to 2.0). This retrospective database analysis is important and […]

Absence of beneficial effect of acute normovolemic hemodilution combined with aprotinin on allogeneic blood transfusion requirements in cardiac surgery.

This prospective randomized study showed that acute normovolemic hemodilution (ANH) did not reduce the risk of allogeneic blood transfusion in elective cardiac surgical patients. However, the interpretation of these results is limited by the fact that ANH was not performed in clinical conditions where its efficacy can be demonstrated: low blood volume collection and reduced […]