Acquired factor VII deficiency in hematopoietic stem cell transplant recipients.

This is an interesting and new case report on the occurrence of acquired factor VII deficiency in eight patients following intensive chemotherapy and/or radiotherapy followed by hematopoietic stem cell transplantation (SCT), associated with serious and sometimes fatal hemorrhagic complications with poor response to transfusion of blood components. Tests for antibodies against FVII were negative. It […]

Intraoperative cell salvage in radical retropubic prostatectomy.

This article attempts a risk evaluation with only 62 patients. Unfortunately, statistics tell us that, even to show a risk increase (e.g., of metastasis) by as much as 10%, one needs more than 1000 patients (Harrison et al., Br J Surg 1992;79:355-357)! In terms of transfusion risks, a level of sensitivity of 10% is out […]

Liver resections with or without pedicle clamping.

The authors demonstrate in a well-thought-out study what we have all suspected based on trauma experience: that temporary clamping of the hepatic pedicle, or the Pringle manouver, can reduce blood loss and the need for transfusion without jeopardizing the patient. – R. K. Spence.

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