Tranexamic acid reduces allogenic transfusion in revision hip arthroplasty.
In this study, the authors retrospectively reviewed revision hip arthroplasties to assess the effectiveness of a Blood Utilization Program, including the use of tranexamic acid, and to determine the variables […]
Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
This is a very important, landmark article describing for the first time the efficacy of an antifibrinolytic, tranexamic acid (TA), to decrease mortality in bleeding trauma patients. The study enrolled […]
Intraoperative low-volume acute normovolemic hemodilution in adult open-heart surgery.
In this prospective randomized study, intraoperative acute isovolemic hemodilution (ANH) was not associated with a reduction in the need for allogeneic blood transfusion. However, this study evaluated the contribution of […]
Effectiveness of combined blood conservation measures in thoracic aortic operations with deep hypothermic circulatory arrest.
Note: See also the useful invited commentary by John A. Elefteriades on pages 743-4. – F. Regan and M. Contreras.