Acute normovolemic hemodilution and intraoperative cell salvage in aortic surgery.

This retrospective study reviews the blood conservation strategy developed in patients undergoing infrarenal aortic surgery in a tertiary vascular unit from 1995 to 2001. The authors show that the judicious association of acute normovolemic hemodilution and intraoperative cell salvage combined with restrictive transfusion triggers and careful surgery can dramatically reduce the use of allogeneic blood […]

Recombinant factor VIIa improves clot formation but not fibrolytic potential in patients with cirrhosis and during liver transplantation.

Etiology of bleeding in cirrhotic patients during surgery is multifactorial, and its management includes several measures such as replacement of coagulation factors and platelets as well as the use of antifibrinolytic agents. Recombinant factor VIIa has been shown to normalize prothrombin time in patients with liver disease and to reduce transfusion requirement during OLT. In […]