Contemporary risk factors and outcomes of transfusion-associated circulatory overload.

Recently, a joint working group of members of the International Haemovigilance Network, the International Society of Blood Transfusion and AABB concluded that it is too early to develop a consensus on TACO, its definition, its reporting criteria and its risk factors. This was due to the fact that currently, insufficient published research was available to […]

Prior red blood cell transfusions in cancer patients increase the risk of subsequent transfusions with or without recombinant human erythropoietin management.

Couture et al. perform an interesting meta-analysis of 5 previously reported, placebo-controlled epoetin alfa studies in anemic cancer patients on chemotherapy. Their conclusions are simple and intuitive: previous blood transfusion and low baseline hemoglobin predict for future blood transfusions. However, I am not sure if their suggestion that earlier treatment with epoetin alfa necessarily prevents […]

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