Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial.
Shakur H, Roberts R, Bautista R, et al.
Lancet 2010;376(9734):23-32.
Review by J.-F. Hardy
Recombinant factor VIIa as adjunctive therapy for bleeding control in severely injured trauma patients: two parallel randomized, placebo-controlled, double-blind clinical trials.
The etiology of severe hemorrhage associated with trauma includes coagulopathy, hypothermia, acidosis, as well as platelet dysfunction, in addition to the direct effect of trauma... Read More
First military use of activated Factor VII in an APC-III pelvic fracture.
Williams DJ, Thomas GO, Pambakian S, Parker PJ
Injury 2005;36(3):395-399.
Review by M. Aldouri
Factor VIIa for correction of traumatic coagulopathy.
Dutton RP, McCunn M, Hyder M, et al.
J Trauma 2004;57(4):709-719.
Review by
A novel hemostatic agent: the potential role of recombinant activated factor VII (RFVIIa) in anesthetic practice.
Murkin JM
Can J Anaesth 2002;49(10):S21-S26.
Review by Aldouri M
HBOC-201 improves survival in a swine model of hemorrhagic shock and liver injury.
Katz LM, Manning JE, McCurdy SL, et al.
Resuscitation 2002;54(1):77-87.
Review by Van der Linden P
Updates in the management of severe coagulopathy in trauma patients.
Lynn M, Jeroukhimov I, Klein Y, Martinowitz U
Intensive Care Med 2002;28(Suppl 2):S241-S247.
Review by Aldouri M
Early use of recombinant factor VIIa improves mean arterial pressure and may potentially decrease mortality in experimental hemorrhagic shock: A pilot study.
Lynn M, Jerokhimov I, Jewelewicz D, et al.
J Trauma 2002;52(4):703-707.
Review by
Release of interleukin-10 by reinfusion of salvaged blood after knee arthroplasty.
Tylman M, Bengtson JP, Avall A, Hyllner M, Bengtsson A
Intens Care Med 2001;27(8):1379-1384.
Review by E. Hansen
Recombinant activated factor VII for adjunctive hemorrhage control in trauma.
Martinowitz U, Kenet G, Segal E, et al.
J Trauma 2001;51(3):431-438.
Review by M. Aldouri
Hypotensive resuscitation using a polymerized bovine hemoglobin-based oxygen-carrying solution (HBOC-201) leads to reversal of anaerobic metabolism.
McNeil JD, Smith DL, Jenkins DH, York GB, Josephs JD
J Trauma 2001;50(6):1063-1075.
Review by
NATA: Network for the Advancement of Patient Blood Management, Haemostasis and Thrombosis
MISSION: Providing a multidisciplinary forum for dialogue between haematologists, transfusion medicine specialists, anaesthesiologists, intensive care and emergency physicians, surgeons, perfusionists, nurses, biomedical scientists and other healthcare professionals.
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