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The effects of a polymerized bovine-derived hemoglobin solution in a rabbit model of arterial thrombosis and bleeding.

Using a well recognized experimental model, the authors demonstrated that polymerized bovine-based hemoglobin solution markedly reduced arterial thrombosis rate and increased bleeding time in rabbits. These results are in contrast with those reported with other hemoglobin-based oxygen carriers. There is increasing evidence that the effects of hemoglobin solutions on hemostasis can be influenced by their […]