Effect of intraoperative fluid management on outcome after intraabdominal surgery.
Another randomized controlled trial demonstrating that the recipe book administration of larger quantities of crystalloid (i.e., 12 ml/kg/hr irresepective of hemodynamics) around the time of major surgery is associated with […]
The influence of crystalloid and colloid replacement solutions in acute normovolemic hemodilution: a preliminary survey of hemostatic markers.
This prospective randomized single blinded study nicely showed the dual effects of plasma substitutes used in acute normovolemic hemodilution. Solutions that have an impact on hemostasis like dextran and high […]
Intraoperative colloid administration reduces postoperative nausea and vomiting and improves postoperative outcomes compared with crystalloid administration.
An important and long awaited addition to the colloid vs crystalloid debate. A blinded, adequately powered PRCT that asks a sensible, hypothesis driven question, i.e., Is there a difference in […]
Intravascular volume replacement therapy with synthetic colloids: is there an influence on renal function?
A good summary of the literature on this frequently asked question. Some excellent tables and a useful citation listing. The important take home message is sadly all too familiar: inadequate […]
Influence of a new hydroxyethylstarch preparation (HES 130/ 0.4) on coagulation in cardiac surgical patients.
Note that volumes of Gelatine and Starch required to maintain CVP are no different between two groups, suggesting that the two solutions are equally effective as plasma volume expanders. However, […]
The effects of hydroxyethyl starches of varying molecular weights on platelet function.
This article is of interest in clinical decision-making related to starches usage. However, its interest is even higher for researchers in the field of volume replacement. – M. Mythen.