Retrograde autologous priming of the cardiopulmonary bypass circuit reduces blood transfusion after coronary artery surgery.
This article confirms previous studies showing that a reduction of the bypass circuit priming volume can be associated with a reduction in allogeneic blood use. This beneficial effect is related to a lower degree of hemodilution reached during and immediately after the cardiopulmonary bypass. – P. Van der Linden
Transfusion in premature infants impairs production and/or release of red blood cells, white blood cells and platelets.
The author concludes that suppression of erythro-, leuko- and thrombopoiesis within 48 hours after transfusion decreases the amount of precursor cells in the peripheral blood. This is a very important observation. However, the question arises as to whether it is not only an inhibition of bone marrow cell release to the peripheral blood. – V. […]
Hypotensive resuscitation using a polymerized bovine hemoglobin-based oxygen-carrying solution (HBOC-201) leads to reversal of anaerobic metabolism.
Interesting article evaluating the place of a hemoglobin-based oxygen-carrying solution in the resuscitation of severe hemorrhagic shock. – P. Van der Linden.