Recombinant activated factor VII: its mechanism of action and role in the control of hemorrhage.
This is an overview on the mechanism of action of rFVIIa and its role in hemostasis. rFVIIa directly activates FX, increases thrombin activation on activated platelets, and leads to generation […]
Use of recombinant factor VIIa in hereditary bleeding disorders.
This is another excellent review of the mechanism of action, indications, and various doses of rFVIIa (Novoseven) in hereditary bleeding disorders. Its main use has been in patients with factor […]