Welcome and Introduction

Dr. Oliver Grottke – Aachen, Germany

Factor I the First to Replace?

Dr. Dietmar Fries – Innsbruck, Austria

Is It Time to Replace Plasma With 4F-PCC in Cardiac Surgery?

Dr. Keyvan Karkouti – Toronto, Canada

Addressing Challenges in Surgery

Dr. Oliver Grottke – Aachen, Germany

Q&A

Learning Objectives:

By the end of this symposium, participants will be able to identify key challenges in surgical bleeding management, understand the rationale for prioritizing early fibrinogen (Factor I) replacement, and evaluate current clinical evidence supporting the use of 4-factor prothrombin complex concentrate (4F-PCC) as a superior option to FP on efficacy and safety for patients undergoing cardiac surgery with coagulopathic bleeding, with the goal of optimizing haemostatic strategies and improving patient outcomes.