In this study, the authors retrospectively reviewed revision hip arthroplasties to assess the effectiveness of a Blood Utilization Program, including the use of tranexamic acid, and to determine the variables […]
This study describes a helpful tool to evaluate and improve platelet transfusion practice in a large academic hospital. – Paolo Rebulla
In this prospective observational study, Jankowska and colleagues evaluated and followed 546 patients with stable systolic chronic heart failure (CHF) and NYHA class I-IV, for the effect of iron deficiency […]
During normovolemic hemodilution, e.g. during the replacement of blood loss with crystalloids and/or colloids in a bleeding patient, the first procoagulant factor that decreases below a level requiring substitution is […]
Volume replacement with so-called “balanced” fluids as opposed to “non-balanced” is a much-discussed and interesting issue. This study confirms what is in essence known: balanced fluids ameliorate certain physiologic parameters. […]
Red blood cells (RBCs) may be stored up to 42 days prior to transfusion. However, RBCs show many changes after storage including increased RBC aggregation, decreased 2,3-diphosphoglycerate levels, loss of […]
This is a randomized control trial of patients undergoing bilateral total knee arthroplasty and presenting with iron deficiency, either absolute (ferritin < 100 g/L) or functional (ferritin 100-300 g/L, transferrin […]
The article by Inaba et al. is a retrospective observational single-center study assessing the impact of FFP transfusion on morbidity and mortality in non-massively transfused trauma patients from 2000 to […]
Jeong et al. review the concept that elevated and elevation of blood viscosity is associated with increased health risk of all forms. As a corollary it is proposed that patient […]
Four famous key opinion leaders in the field of venous thromboembolism (VTE) prevention have performed a critical appraisal of bleeding events reported in VTE prophylaxis trials of patients undergoing hip […]
Since the withdrawal of aprotinin from the market in 2007 and the replacement by lysine analogs, there are divergent opinions about increased bleeding tendencies after major cardiac surgery. In this […]
This case report describes a fatal outcome after application of rFVIIa in combination with PCC in a bleeding patient after heart transplantation treated with ECMO. The patient was in desperate […]
The second edition of the NATA textbook, entitled Alternatives to Blood Transfusion in Transfusion Medicine and co-edited by Prof. Alice Maniatis, Prof. Philippe Van der Linden and Prof. Jean-Francois Hardy, […]
This is an interesting multicenter, retrospective, cohort study of RBC transfusion in major orthopedic surgery (n = 701 arthroplasties) performed in three different hospitals in Canada. The authors couldnt find […]
Wu and colleagues have conducted an elegant observational study evaluating the effect of intraoperative transfusion on 30-day mortality in elderly patients (≥ 65 years) undergoing non-cardiac surgery. Standardized, prospective data […]