Association of blood component ratios with 24-hour mortality in injured children receiving massive transfusion.
While the incidence of paediatric trauma requiring massive transfusion is lower than the incidence in adults, little is known regarding the optimal transfusion strategy in the paediatric population. Although optimal […]
4-factor prothrombin complex concentrate is associated with improved survival in trauma related hemorrhage: a nationwide propensity matched analysis.
The authors conducted a retrospective study to evaluate outcomes of severely injured trauma patients who received 4-factor prothrombin complex concentrate (4-PCC) + fresh frozen plasma (FFP) compared to FPP alone. […]
Fibrinogen concentrate as an alternative to cryoprecipitate in a postcardiopulmonary transfusion algorithm in infants undergoing cardiac surgery: a prospective randomized controlled trial.
This is an excellent multicentre prospective randomised trial evaluating the efficacy of fibrinogen concentrate (FC) compared to cryoprecipitate to achieve haemostasis for infants post-cardiopulmonary bypass. The primary outcome was the […]
A regional massive hemorrhage protocol developed through a modified Delphi technique.
The authors noted that large academic centres are very likely to have a massive haemorrhage protocol (MHP) but smaller non-academic hospitals may not. Using a Modified Delphi Method, they convened […]
The effect of anemia severity on postoperative morbidity among patients undergoing laparoscopic hysterectomy for benign indications.
This is a very well-designed retrospective study using a large American surgical database (NISQP) reporting the a high incidence of anaemia (19.5%) in patients undergoing elective laparoscopic hysterectomy. The following […]
Impact of a Patient Blood Management monitoring and feedback programme on allogeneic blood transfusions and related costs.
While Patient Blood Management (PBM) is becoming a new standard worldwide with evidence-based and expert consensus guidelines to promote the three PBM pillars, measuring the performance of these efforts remains […]
Perioperative management of patients with atrial fibrillation receiving a direct oral anticoagulant.
The Perioperative Anticoagulation Use for Surgery Evaluation (PAUSE) cohort study enrolled 3007 atrial fibrillation patients treated with apixaban, dabigatran etexilate or rivaroxaban and scheduled for an elective surgery or procedure. A […]
Obstetric intra-operative cell salvage: a review of an established cell salvage service with 1170 re-infused cases.
This is a retrospective report of 10 years of obstetrical cell salvage use in a single hospital. The authors report on 1170 patients who had a median of 231 mL of blood […]