The effects of a polymerized bovine-derived hemoglobin solution in a rabbit model of arterial thrombosis and bleeding.
Using a well recognized experimental model, the authors demonstrated that polymerized bovine-based hemoglobin solution markedly reduced arterial thrombosis rate and increased bleeding time in rabbits. These results are in contrast […]
Autologous blood sequestration using a double venous reservoir bypass circuit and polymerized hemoglobin prime.
This experimental study describes a modified cardiopulmonary bypass circuit using a bovine hemoglobin solution priming that protects a portion of the autologous blood volume from the damaging effects of bypass. […]
Polymerized bovine hemoglobin solution as a replacement for allogeneic red blood cell transfusion after cardiac surgery: results of a randomized, double-blind trial.
The article by Jerrold Levy et al. is one of the few randomized controlled trials published on the use of hemoglobin-based oxygen-carrying (HBOC) solutions in patients. Similarly to the study […]