Tag: CHILDREN

Tandem high-dose therapy (HDT) for multiple myeloma: recombinant human erythropoietin therapy given between first and second HDT allows second peripheral blood stem cell transplantation without red blood cell transfusion.

This is a very interesting and noteworthy study. We know that autologous transplants can cause severe anemia, but we also know that EPO therapy does not work well in the […]

Recombinant human erythropoietin in pediatric oncology: a review.

Important to attempt review, but too much variability in studies to form meaningful conclusion. – Patricia Ford

Continuous infusion of coagulation factor products.

This is an interesting review on the use of continuous infusion of coagulation factor products over the last 11 years. It concludes that effects were favorable in comparison to intermittent […]

Rationale for the use of high dose rFVIIa in a high-titre inhibitor patient with haemophilia B during major orthopaedic procedures.

This is a case report of a child with severe hemophilia B and high titer factor IX inhibitor who was not achieving good hemostasis on conventional doses of rFVIIa. Pharmacokinetic […]

Usefulness of cord-blood harvesting for autologous transfusion in surgical newborns with antenatal diagnosis of congenital anomalies.

In connection with this study, one may wonder how often, in those children needing blood transfusions, the volume of cord blood collected will be sufficient to avoid allogeneic transfusions. Besides, […]