Effect of intraoperative fluid management on outcome after intraabdominal surgery.
Another randomized controlled trial demonstrating that the recipe book administration of larger quantities of crystalloid (i.e., 12 ml/kg/hr irresepective of hemodynamics) around the time of major surgery is associated with […]
A comparison of albumin and saline for fluid resuscitation in the intensive care unit.
Essential reading material. The largest PRCT of Albumin vs Saline in 7,000 critically ill patients in Australia and New Zealand. Concludes “no-difference” in 28 day mortality. Subset trends to excess […]
The influence of crystalloid and colloid replacement solutions in acute normovolemic hemodilution: a preliminary survey of hemostatic markers.
This prospective randomized single blinded study nicely showed the dual effects of plasma substitutes used in acute normovolemic hemodilution. Solutions that have an impact on hemostasis like dextran and high […]
Intraoperative colloid administration reduces postoperative nausea and vomiting and improves postoperative outcomes compared with crystalloid administration.
An important and long awaited addition to the colloid vs crystalloid debate. A blinded, adequately powered PRCT that asks a sensible, hypothesis driven question, i.e., Is there a difference in […]
Comparison of the effects of a 50% exchange-transfusion with albumin, hetastarch, and modified hemoglobin solutions.
This preliminary (considering phase III studies have been completed or are underway) study in rats adds little to what has already been published on this issue in more elaborate animal […]