Effect of fasting on coagulation factors in patients who undergo major abdominal surgery.
This is a highly peculiar study in which patients undergoing major abdominal surgery had to abstain from eating 9 days before the operation. To make things worse, they were not […]
Blood still kills: six strategies to further reduce allogeneic blood transfusion-related mortality.
In this article, Vamvakas and Blajchman, in a “tour de force”, reviewed the causes of allogeneic transfusion-related mortality as documented in more than 300 publications! The three leading causes in […]
Cell salvage for minimising perioperative allogeneic blood transfusion.
This recent Cochrane analysis underlines the benefits of cell salvage in orthopedic and cardiac surgery. There is a 21% absolute risk reduction in RBC usage without any clinical adverse event. […]
Pulmonary effects of red blood cell transfusion in critically ill, non-bleeding patients.
This retrospective study reported a degradation of the PaO2/FiO2 ratio (from 250 105 to 240 102; p = 0.003) on the first day after RBC transfusion in 83 non-bleeding ICU […]
A pilot study of the possibility and the feasibility of haemoglobin dosing with red blood cells transfusion.
The present study describes a model to predict a patient’s hemoglobin (Hb) increment after transfusion of 1 or more RBC units with a known Hb content. The pilot study has, […]
Severe hypotension related to cell salvaged blood transfusion in obstetrics.
There has been much debate about the use of cell salvage in the obstetric patient because of potential complications associated with fetal contamination and possible amniotic fluid embolism. This report […]
The prevalence of anemia and its association with 90-day mortality in hospitalized community-acquired pneumonia.
The two recent articles reviewed herein emphasize that anemia in hospitalized patients identifies patients with greater risk of death or complications. Kurek and colleagues from Poland followed consecutive patients with […]
Moderate exposure to allogeneic blood products is not associated with reduced long-term survival after surgery for coronary artery disease.
Weightman and colleagues have conducted a longitudinal analysis of 1,841 consecutive patients undergoing primary coronary artery surgery followed for a mean of just over 8 years. Their analysis revealed no […]
Low oxygen-affinity hemoglobin solution increases oxygenation of partially ischemic tissue during acute anemia.
This is the first quantitative experimental proof of the concept of targeted oxygen delivery to ischemic tissue by polymerized bovine hemoglobin (Hb). This Hb solution is commercially available, but clinically […]
Effect of anemia in high-risk groups of patients with acute myocardial infarction treated with percutaneous coronary intervention.
The two recent articles reviewed herein emphasize that anemia in hospitalized patients identifies patients with greater risk of death or complications. Kurek and colleagues from Poland followed consecutive patients with […]
A prospective randomised multicentre clinical comparison of a minimised perfusion circuit versus conventional cardiopulmonary bypass.
This prospective randomized multicenter study reported that minimized perfusion circuit (MPC) is associated with a lower transfusion rate and and a lower incidence of postoperative atrial fibrillation in comparison to […]
When and why is blood crossmatched?
This is a very topical article. Since a high proportion of hazards of transfusion in several Hemovigilance programs show that a significant number are due to errors, particularly of giving […]
FDA report: Ferumoxytol for intravenous iron therapy in adult patients with chronic kidney disease.
It is well known that intravenous iron offers an effective, feasible route towards reducing the heavy burden of iron-deficiency anemia in both dialysis and non-dialysis CKD patients, even in the […]
Mid-term to long-term clinical and functional outcomes of minimally invasive correction and fusion for adults with scoliosis.
In their retrospective analysis, Anand and coworkers report the effects of minimally invasive percutaneous spine surgery (scoliosis correction) on blood loss, hospital length of stay and functional outcome in 28 […]
The PROTON study: profiles of blood product transfusion recipients in the Netherlands.
This paper from the Netherlands is very important in view of estimating the future use of blood products and to observe the well-known variations in the use of blood products […]