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Recombinant factor VIIa improves clot formation but not fibrolytic potential in patients with cirrhosis and during liver transplantation.

Etiology of bleeding in cirrhotic patients during surgery is multifactorial, and its management includes several measures such as replacement of coagulation factors and platelets as well as the use of antifibrinolytic agents. Recombinant factor VIIa has been shown to normalize prothrombin time in patients with liver disease and to reduce transfusion requirement during OLT. In […]

Successful outcome of a cirrhotic patient with postoperative haematuria treated with a single high dose of recombinant factor VIIa.

Etiology of bleeding in patients with liver disease is multifactorial, and there has been variable response to treatment with rFVIIa, although correction of prolonged prothrombin time in such patients has been reported. This is a case report of a cirrhotic patient who developed intractable hematuria following urinary bladder tumor resection in spite of transfusion of […]