The use of recombinant factor VIIa for severe intractable bleeding during spine surgery.

This is a report on the effective use of rFVIIa in controlling postoperative surgical bleeding and coagulopathy in four patients who underwent multilevel spine surgery. Bleeding was not initially controlled with the use of local measures and transfusion of blood components. Three patients required a single dose, and one received 2 doses. RFVIIa doses ranged […]