Patient safety and blood transfusion: new solutions.
Interesting paper on new solutions for making transfusions safer. The only aspect which is missing is a better education of the staff involved in hemotherapy, which is even more important […]
Tag: THERAPY
Effect of recombinant human erythropoietin on quality of life in cancer patients receiving chemotherapy: Results of a randomized, controlled trial.
A nice demonstration again in a placebo controlled trial that recombinant EPO is safe and effective in anemic cancer patients on chemorx. The three times weekly dose is more commonly […]
Managing uncontrolled hemorrhage in trauma and surgery: a novel and promising approach.
This is an introduction for a supplement to the Canadian Journal of Anesthesia reporting proceedings of a satellite symposium presented at the 2002 Canadian Anesthesiologists’ Society Annual Meeting. It highlights […]
Combining anchor and distribution-based methods to derive minimal clinically important differences on the functional assessment of cancer therapy (FACT) anemia and fatigue scales.
This helpful article offers increased understanding and ability to utilize the functional assessment of cancer therapy (FACT) scale. – Patricia Ford
Response predicting factors to recombinant human erythropoietin in cancer patients undergoing platinum-based chemotherapy.
This is a well done study of anemic cancer patients on cisplatin chemotherapy that documents nicely that the best predictor of an ultimate good response to epoetin is an early […]
Continuous infusion of coagulation factor products.
This is an interesting review on the use of continuous infusion of coagulation factor products over the last 11 years. It concludes that effects were favorable in comparison to intermittent […]
Experience with use of recombinant activated factor VII.
This is a case report of successfully treating hemorrhage with rFVIIa in four patients with factor VIII and one with factor V inhibitor. One patient was initially treated with APCC […]
Nontransferrin-bound iron in the plasma of haemodialysis patients after intravenous iron saccharate infusion.
This is a very important study as it has long been debated whether relevant amounts of free iron circulate after the administration of parenteral iron. The study confirms that this […]
Efficacy of a low-dose intravenous iron sucrose regimen in peritoneal dialysis patients.
The authors evaluated a low dose iron substitution scheme for the effectiveness in patients with peritoneal dialysis: 50 mg iron sucrose every other week is effective in patients with ferritin […]
Epinephrine versus epinephrine plus fibrin glue injection in peptic ulcer bleeding: a prospective randomized trial.
A useful study (notwithstanding power) and review of current practices. – F. Regan and M. Contreras.
Effective hemostasis with rFVIIa treatment in two patients with severe thrombocytopenia and life-threatening hemorrhage.
This article reports 2 patients with severe thrombocytopenia and severe hemorrhage which did not respond to standard therapy and platelet transfusion, but responded quickly to administration of a single dose […]
Recombinant factor VIIa in the management of surgery and acute bleeding episodes in children with haemophilia and high responding inhibitors.
This study reports the effective use of rFVIIa in covering 20 surgical procedures in 12 patients with hemophilia VIII with high inhibitors, in addition to treating 6 episodes of severe […]
Reduction in erythropoietin doses by the use of chronic intravenous iron supplementation in iron-replete hemodialysis patients.
The authors from Taiwan state that they used “Ferrum Hausmann, a ferric polymaltose complex.” Under the same name (Ferrum Hausmann), iron saccharate (identical to iron sucrose) has been licensed in […]
Iron administration and clinical outcomes in hemodialysis patients.
This study raises two important questions: First, are the observed adverse events upon high dose iron dextran users due to confounding variables such as comorbidity, or are they true iron […]
Surgery-associated acquired hemophilia A.
This article raises awareness of the occurrence of acquired FVIII inhibitor postoperatively. One patient developed an inhibitor to FVIII 4 days after surgery for correction of abdominal hernia and bleeding […]