The association of lowest hematocrit during cardiopulmonary bypass with acute renal injury after coronary artery bypass surgery.
Challenging data about correlation between hemodilution and acute renal injury (documented by increase of creatinine), however, seems only to be relevant in patients with overweight. – Volker Kretschmer
Risk of recurarization during retransfusion of autologous blood withdrawn after injection of muscle relaxants: A comparison of rocuronium and mivacurium.
Important information concerning the risk of recurarization when mivacurium and rocuronium have been administered prior to the removal of autologous blood in ANH. The anesthetist should be aware of this […]
Hydroxyethyl starch (HES) 130/0.4 provides larger and faster increases in tissue oxygen tension in comparison with prehemodilution values than HES 70/0.5 or HES 200/0.5 in volunteers undergoing acute normovolemic hemodilution.
This prospective randomized double-blinded crossover study demonstrated that hydroxyethyl starch specifications (in vitro molecular weight, degree and pattern of substitution) could significantly alter muscular tissue oxygen tension used as an […]
Perfluorochemical ”red blood cell substitutes”: the continued search for an indication. [Editorial]
The author criticizes, quite rightly and not without reason, the study by Spahn et al. on a number of issues. However, he recognizes that, at the end of the day, […]
The in vitro effects of crystalloids and colloids on coagulation.
Worth a close look for those with a specialist interest in this area. Adds to a fast growing body of literature on the various effects of i.v. solutions on coagulation […]
Mild hypothermia has minimal effects on the tolerance to severe progressive normovolemic anemia in swine.
This experimental study performed in anesthetized pigs reports that hypothermia to 32C did not really improve tolerance to acute dilutional anemia as reflected by a non significant change in the […]
The novel HemoCue (R) Plasma/Low Hemoglobin System accurately measures small concentrations of three different hemoglobin-based oxygen carriers in plasma.
Clinical accuracy and reliability of the currently available Hemocue(R) B-Hemoglobin Photometer has been demonstrated for large concentrations of hemoglobin from human and bovine origin. Using a new version of the […]
Blood substitute and erythropoietin therapy in a severely injured Jehovah’s witness.
Our comments were published in a letter to the Editor (see Hardy JF, Belisle S, Van der Linden P. Combined blood substitute and eryth-ropoietin therapy in a severely injured Jehovah’s […]
The theory and practice of bloodless surgery.
A very thorough overview of all aspects of blood-sparing methods. – V. Kretschmer
Perioperative blood salvage as an alternative to predonating blood for primary total knee and hip arthroplasty.
This retrospective study shows again that intra- and postoperative blood salvage can minimize allogeneic transfusions. For the recent discussion about the use of unwashed drainage blood the paper is remarkable […]
Effects of ultra-purified polymerized bovine hemoglobin on local tissue oxygen tension in striated skin muscle – An efficacy study in the hamster.
This is another study on the potential benefits of an oxygen carrier (ultrapurified polymerized bovine hemoglobin solution) on tissue perfusion after hypervolemic infusion or exchange transfusion of 50% of blood […]
Are lactated Ringer’s solution and normal saline solution equal with regard to coagulation?
This study compares the perioperative effects of a saline crystalloid and a more balanced and buffered electrolyte crystalloid on clotting. The differences thought to be related to blood clotting that […]
Comparison of the effects of a 50% exchange-transfusion with albumin, hetastarch, and modified hemoglobin solutions.
This preliminary (considering phase III studies have been completed or are underway) study in rats adds little to what has already been published on this issue in more elaborate animal […]
Hemostatic changes in patients receiving hydroxyethyl starch: The influence of ABO blood group.
This article is of interest in clinical decision-making related to starches usage. However, its interest is even higher for researchers in the field of volume replacement. – M. Mythen.