This is an interesting multicenter, retrospective, cohort study of RBC transfusion in major orthopedic surgery (n = 701 arthroplasties) performed in three different hospitals in Canada. The authors couldnt find […]
This prospective single-blind study reports that, in comparison to Ringer acetate, both 6% HES 130/0.4 and 4% modified fluid gelatin administered postoperatively impair clot formation and strength in a dose-related […]
The authors conducted an experimental study in rat traumatic brain injury showing that colloids lead to lesser brain edema. The study was well conducted but, obviously, clinical studies are needed […]
In order to evaluate the incidence and risk factors for the development of anemia after Roux-en-Y gastric bypass (RYGB), the authors performed a retrospective analysis of 206 patients who received […]
The authors conducted a prospective, pre- (93 patients) and post-intervention (347 patients) study to evaluate a new transfusion strategy designed to reduce the rate of allogeneic transfusion and promote single-unit […]
This is a very important, landmark article describing for the first time the efficacy of an antifibrinolytic, tranexamic acid (TA), to decrease mortality in bleeding trauma patients. The study enrolled […]
In this commentary, the authors provide a nice overview of pathogen reduction technology (PRT). The necessity of 6 log PRT technique is discussed. The figures underline the viral replication including […]
The article by Mell et al. is a retrospective observational single-center study assessing the relationship between transfusion ratios of PRBC:FFP and mortality in patients undergoing operative repair of ruptured abdominal […]
This retrospective observational single-center study confirms a high prevalence of preoperative anemia (36.5%) in patients scheduled for elective cardiac surgery. Anemia is clinically relevant because it was associated with increased […]
The article by Bower is yet another observational study assessing the relationship between transfusion and serious morbidity and/or mortality in patients undergoing non-cardiac surgery. A single-center academic hospital experience of […]
The authors conducted a systematic review of plasma transfusion in common clinical settings. Plasma transfusion was beneficial only in the setting of massive transfusion. However, the underlying evidence was of […]
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In the article entitled “Safety and current status of blood transfusion in China”, Yu et al. describe the difficulties in blood procurement and blood conservation in the Beijing area. Because […]
The authors used a mouse model to examine the effect of RBC transfusion on adverse outcomes related to free iron and inflammation. They hypothesized that acute clearance of damaged RBCs […]
The authors conducted an audit of plasma transfusion practice in their hospital network. The data date back to 2006 and appropriateness of transfusion was based on 1994 recommendations. Nevertheless, given […]